Analgesics, Antidepressants, Antiinflammatory drugs, Applications at pH extremes (1-11), Decreased retention of non-polar compounds, Herbicide, Ideal for method development, Immunosuppressants, Pharmaceuticals, Phytopharmaceuticals, RP applications HPLC, Similar to NUCLEODUR C18 Gravity, Suitable for LC-MS
Storage temperature
RT
Scope of delivery
1x analytical HPLC column, instruction leaflet, certificate of analysis
Hazardous material
No
Method
HPLC, analytical
Brand
NUCLEODUR
Base material
NUCLEODUR - high purity silica
Phase
NUCLEODUR C8 Gravity
USP listing
L7
Surface chemistry
Base deactivated (BDS), High density monomeric octyl (C8, MOS) modification
Mode
Reversed phase (RP)
Type
EC HPLC column (analytical)
Hardware
Stainless steel
Column length
250 mm
Column inner diameter
3 mm
Particle type
Fully porous particles (FPP)
Particle shape
Spherical
Particle size
5 µm
Eluent in HPLC column
Acetonitrile – water
Endcapped
Yes
Carbon content
11.0 %
pH stability
1.0–11.0
Pore size
110 Å
Specific surface according to BET
340 m²/g
Temperature stability (max)
60 °C
Pressure stability (max)
600 bar
Column volume
1.75 mL
DESCRIPTION
This high density C8 phase based on high purity NUCLEODUR silica gel with its endcapping suppresses any unwanted polar interactions between the silica surface and the sample, which makes “Gravity” particularly suitable for the separation of basic and other ionizable analytes. Due to the enhanced pH stability, LC/MS suitability and superior base deactivation (BDS) it is a perfect choice for method development and valuable for RP applications.