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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL877250-101 ZORBAX Rx-Sil, PrepHT cartridge, 21.2, 250 mm, 7 µm (use with hardware kit 820400-901) 2203 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 250 mm
  • Phase
  • Rx-SIL
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L3
  • Brand
  • ZORBAX
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • LC Platform
  • Preparative HPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 7 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0.8-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 350 bar
  • Separation Mode
  • Normal Phase SFC
AGIL877250-106 ZORBAX Rx, PrepHT cartridge, Rx-C8, 21.2, 250 mm, 7 µm (use with hardware kit 820400-901) 3363 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 250 mm
  • Phase
  • Rx-C8
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Carbon Load
  • 5.5 %
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 7 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 340 bar
  • Separation Mode
  • Reversed Phase
AGIL880967-202 ZORBAX Rx 80Å C18, 9.4 x 250 mm, 5 µm HPLC column 1659 
Add to Cart
  • Inner Diameter (ID)
  • 9.4 mm
  • Length
  • 250 mm
  • Phase
  • C18
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Carbon Load
  • 12 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-860 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 350 bar
  • Separation Mode
  • Reversed Phase
AGIL880967-902 ZORBAX Rx-C18, 80Å, 4.6 x 250 mm, 5 µm, 400 bar pressure limit 706 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 250 mm
  • Phase
  • Rx-C18
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Carbon Load
  • 12 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-860 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL880975-201 ZORBAX Rx-SIL 5 µm, 9.4 x 250 mm 1659 
Add to Cart
  • Inner Diameter (ID)
  • 9.4 mm
  • Length
  • 250 mm
  • Phase
  • Rx-SIL
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L3
  • Brand
  • ZORBAX
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Conventional
  • LC Platform
  • Preparative HPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0.8-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 350 bar
  • Separation Mode
  • Normal Phase SFC
AGIL883700-901 ZORBAX Rx-SIL, 80Å, 2.1 x 150 mm, 5µm, 400 bar pressure limit 645 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 150 mm
  • Phase
  • Rx-SIL
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L3
  • Brand
  • ZORBAX
  • Carbon Load
  • 0 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0.8-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Normal Phase SFC
  • Shipping Solvent
  • Hexane
AGIL883700-902 ZORBAX Rx-C18, 80Å, 2.1 x 150 mm, 5 µm, 400 bar pressure limit 645 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 150 mm
  • Phase
  • Rx-C18
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX
  • Carbon Load
  • 12 %
  • Endcapped
  • No
  • Guard Column
  • No
  • Hardware
  • Conventional
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-860 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL299-2002 GPC/SEC column frits, 2 µm, 8 mm column ID. Compatible with GRAM, MAB, MCX, NOVEMA Max, PFG, PolarSil, POLEFIN, PROTEEMA, SDV, SUPREMA, EasyValid 8 mm ID columns, 6/pk 115 
Add to Cart
  • UNSPSC Code
  • 41115716
AGIL299-2003 GPC/SEC column frits, Ti, 8 mm column ID. Compatible with GRAM, MAB, MCX, NOVEMA Max, PFG, PolarSil, POLEFIN, PROTEEMA, SDV, SUPREMA, EasyValid 8 mm ID columns, 2/pk 115 
Add to Cart
  • UNSPSC Code
  • 41115716
AGIL299-2006 GPC/SEC column frits, PEEK/Ti, 20 mm column ID. Compatible with GRAM, MCX, NOVEMA Max, SDV, SUPREMA 20 mm ID columns, 2/pk 72 
Add to Cart
  • UNSPSC Code
  • 41115716

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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