DESCRIPTION
The Octet® SPR COOH1 sensor chip is comprised of a 2D planar, carboxylated oligoethylene oxide surface which can be used to create a highly stable covalent bond between the sensor chip and desired ligand. The lack of 3D matrix results in a low binding capacity which allows interactions to take place closer to the sensor chip surface. The potential for non-specific binding to positively charged analytes is decreased due to lack of a carboxymethylated dextran matrix. These sensor chips can also be used if interactions are affected by the presence of lectin or dextran.
Top Features of the Octet® SPR COOH1 Sensor Chip:
Low binding capacity
Covalent coupling
Matrix length from gold surface: ~2 nm
Minimal distance between analyte and planar surface for highly sensitive interactions
Popular Applications for the Octet® SPR COOH1 Sensor Chip:
Intermediate and large molecules
Kinetics
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css@gugent.com.hk
