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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
POA080520 POLEFIN, 8 x 50 mm, 20 µm. GPC/SEC guard column, ships in xylene 591 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 50 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • POLEFIN
  • Guard Column
  • Yes
  • Maximum Temperature
  • 200 °C
  • Particle Size
  • 20 µm
  • Pressure Rating
  • 80 bar
  • Shipping Solvent
  • Xylene
POA083010LIM POLEFIN, Linear-M, 8 x 300 mm, 10 µm. GPC/SEC column, molecular weight range 100 to 10^6, ships in xylene 1900 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • POLEFIN
  • Guard Column
  • No
  • Maximum Temperature
  • 200 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 10 µm
  • Particle Type
  • Mixed Pore Size
  • Pressure Rating
  • 80 bar
  • Shipping Solvent
  • Xylene
POA083010LXL POLEFIN, Linear-XL, 8 x 300 mm, 10 µm. GPC/SEC column, molecular weight range 1000 to 3x10^7, ships in xylene 1900 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • POLEFIN
  • Guard Column
  • No
  • Maximum Temperature
  • 200 °C
  • Molecular Weight Lower Limit
  • 1000 Da
  • Particle Size
  • 10 µm
  • Particle Type
  • Mixed Pore Size
  • Pressure Rating
  • 80 bar
  • Shipping Solvent
  • Xylene
POA083020LXL POLEFIN, Linear-XL, 8 x 300 mm, 20 µm. GPC/SEC column, molecular weight range 1000 to 3x10^7, ships in xylene 1900 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • POLEFIN
  • Guard Column
  • No
  • Maximum Temperature
  • 200 °C
  • Molecular Weight Lower Limit
  • 1000 Da
  • Particle Size
  • 20 µm
  • Particle Type
  • Mixed Pore Size
  • Pressure Rating
  • 80 bar
  • Shipping Solvent
  • Xylene
PSA0830053E2 PolarSil, 300Å, 8 x 300 mm, 5 µm. GPC/SEC column, molecular weight range 1000 to 3x10^5, ships in DMAc 1959 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • PolarSil
  • Guard Column
  • No
  • Maximum Temperature
  • 70 °C
  • Molecular Weight Lower Limit
  • 1000 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Individual Pore Size
  • Pore Size
  • 300 µm
  • Pressure Rating
  • 120 bar
  • Shipping Solvent
  • DMAc
SDA080503LS SDV Lux, 8 x 50 mm, 3 µm. GPC/SEC guard column, ships in THF, pre-equilibrated for use with light scattering detectors 672 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 50 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • SDV
  • Guard Column
  • Yes
  • Maximum Temperature
  • 100 °C
  • Particle Size
  • 3 µm
  • Pressure Rating
  • 150 bar
  • Shipping Solvent
  • THF
SDA080520 SDV, 8 x 50 mm, 20 µm. GPC/SEC guard column, ships in THF 591 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 50 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • SDV
  • Guard Column
  • Yes
  • Maximum Temperature
  • 100 °C
  • Particle Size
  • 20 µm
  • Pressure Rating
  • 60 bar
  • Shipping Solvent
  • THF
SDA0830031E2 SDV, 100Å, 8 x 300 mm, 3 µm. GPC/SEC column, molecular weight range 100 to 10^4, ships in THF 2261 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • SDV
  • Guard Column
  • No
  • Maximum Temperature
  • 100 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 3 µm
  • Particle Type
  • Individual Pore Size
  • Pore Size
  • 100 µm
  • Pressure Rating
  • 150 bar
  • Shipping Solvent
  • THF
SDA0830031E3 SDV, 1000Å, 8 x 300 mm, 3 µm. GPC/SEC column, molecular weight range 100 to 6x10^4, ships in THF 2261 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • SDV
  • Guard Column
  • No
  • Maximum Temperature
  • 100 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 3 µm
  • Particle Type
  • Individual Pore Size
  • Pore Size
  • 1000 µm
  • Pressure Rating
  • 150 bar
  • Shipping Solvent
  • THF
SDA0830035E2 SDV, 500Å, 8 x 300 mm, 3 µm. GPC/SEC column, molecular weight range 100 to 3x10^4, ships in THF 2261 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • SDV
  • Guard Column
  • No
  • Maximum Temperature
  • 100 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 3 µm
  • Particle Type
  • Individual Pore Size
  • Pore Size
  • 500 µm
  • Pressure Rating
  • 150 bar
  • Shipping Solvent
  • THF

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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