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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
NMP2005 NOVEMA Max, 20 x 50 mm, 20 µm. GPC/SEC guard column, ships in water 1326 
Add to Cart
  • Inner Diameter (ID)
  • 20 mm
  • Length
  • 50 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • NOVEMA Max
  • Guard Column
  • Yes
  • Maximum Temperature
  • 80 °C
  • Particle Size
  • 20 µm
  • pH Range
  • 2-12
  • Pressure Rating
  • 80 bar
  • Shipping Solvent
  • Water
NMP20301E2 NOVEMA Max, 100Å, 20 x 300 mm, 20 µm. GPC/SEC column, molecular weight range 100 to 3x10^5, ships in water 4718 
Add to Cart
  • Inner Diameter (ID)
  • 20 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • NOVEMA Max
  • Guard Column
  • No
  • Maximum Temperature
  • 80 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 20 µm
  • Particle Type
  • Individual Pore Size
  • pH Range
  • 2-12
  • Pore Size
  • 100 µm
  • Pressure Rating
  • 80 bar
  • Shipping Solvent
  • Water
NMP20301E3 NOVEMA Max, 1000Å, 20 x 300 mm, 20 µm. GPC/SEC column, molecular weight range 1000 to 10^6, ships in water 4718 
Add to Cart
  • Inner Diameter (ID)
  • 20 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • NOVEMA Max
  • Guard Column
  • No
  • Maximum Temperature
  • 80 °C
  • Molecular Weight Lower Limit
  • 1000 Da
  • Particle Size
  • 20 µm
  • Particle Type
  • Individual Pore Size
  • pH Range
  • 2-12
  • Pore Size
  • 1000 µm
  • Pressure Rating
  • 80 bar
  • Shipping Solvent
  • Water
NMP2030LIS NOVEMA Max, Linear-S, 20 x 300 mm, 20 µm. GPC/SEC column, molecular weight range 100 to 10^5, ships in water 5181 
Add to Cart
  • Inner Diameter (ID)
  • 20 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • NOVEMA Max
  • Guard Column
  • No
  • Maximum Temperature
  • 80 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 20 µm
  • Particle Type
  • Mixed Pore Size
  • pH Range
  • 2-12
  • Pressure Rating
  • 80 bar
  • Shipping Solvent
  • Water
PFA080505 PFG, 8 x 50 mm, 5 µm. GPC/SEC guard column, ships in THF 591 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 50 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • PFG
  • Guard Column
  • Yes
  • Maximum Temperature
  • 70 °C
  • Particle Size
  • 5 µm
  • Pressure Rating
  • 200 bar
  • Shipping Solvent
  • THF
PFA0830071E3 PFG, 1000Å, 8 x 300 mm, 7 µm. GPC/SEC column, molecular weight range 10^4 to 10^6, ships in THF 2027 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • PFG
  • Guard Column
  • No
  • Maximum Temperature
  • 70 °C
  • Molecular Weight Lower Limit
  • 10000 Da
  • Particle Size
  • 7 µm
  • Particle Type
  • Individual Pore Size
  • Pore Size
  • 1000 µm
  • Pressure Rating
  • 100 bar
  • Shipping Solvent
  • THF
PFA083007LXL PFG, Linear-XL, 8 x 300 mm, 7 µm. GPC/SEC column, molecular weight range 100 to 3x10^6, ships in THF 2223 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 300 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • PFG
  • Guard Column
  • No
  • Maximum Temperature
  • 70 °C
  • Molecular Weight Lower Limit
  • 100 Da
  • Particle Size
  • 7 µm
  • Particle Type
  • Mixed Pore Size
  • Pressure Rating
  • 100 bar
  • Shipping Solvent
  • THF
PL1112-1802 PLRP-S 1000Å, 7.5 x 50 mm, 8 µm 876 
Add to Cart
  • Inner Diameter (ID)
  • 7.5 mm
  • Length
  • 50 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 200 °C
  • Particle Size
  • 8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 1000 Å
  • Pressure Rating
  • 207 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC
PL1112-1803 PLRP-S 4000Å, 7.5 x 50 mm, 8 µm 876 
Add to Cart
  • Inner Diameter (ID)
  • 7.5 mm
  • Length
  • 50 mm
  • Phase
  • DVB
  • UNSPSC Code
  • 41115711
  • Brand
  • PLRP-S
  • Hardware
  • SS
  • LC Platform
  • Stainless Steel
  • Maximum Temperature
  • 200 °C
  • Particle Size
  • 8 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-14
  • Pore Size
  • 4000 Å
  • Pressure Rating
  • 207 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC
POA080510 POLEFIN, 8 x 50 mm, 10 µm. GPC/SEC guard column, ships in xylene 591 
Add to Cart
  • Inner Diameter (ID)
  • 8 mm
  • Length
  • 50 mm
  • UNSPSC Code
  • 41115709
  • Brand
  • POLEFIN
  • Guard Column
  • Yes
  • Maximum Temperature
  • 200 °C
  • Particle Size
  • 10 µm
  • Pressure Rating
  • 80 bar
  • Shipping Solvent
  • Xylene

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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