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Agilent offers the largest, most modern liquid chromatography (LC) column portfolios for small molecule analysis, with columns suitable for nearly all separation modes and applications.


Whether you are performing conventional or ultra-fast chromatography, separating biomolecules, or analyzing complex compounds, the industry’s highest-performing compounds deliver fast, reproducible results – all engineered with unparalleled quality and reliability.

Catalog No. Product Net Price
AGIL897250-106 ZORBAX StableBond 300 C8, 21.2 x 250 mm, 7 µm, cartridge (PrepHT). 300 Å pore size. Requires cartridge hardware kit, p/n 820400-901. 3477 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 250 mm
  • Phase
  • 300SB-C8
  • UNSPSC Code
  • 41115709
  • Brand
  • ZORBAX 300SB-C8
  • Hardware
  • SS
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 80 °C
  • Part Number Application
  • Monoclonal Antibodies (mABs) PeptidesProteins
  • Part Number Application Domain
  • Biopharma
  • Particle Size
  • 7 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 300 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
  • Shipping Solvent
  • Acetonitrile/Water
  • Technique
  • LC LC & LC/MS
AGIL970050-906 ZORBAX Eclipse XDB-C8, 21.2, 50 mm, 5 µm (use with hardware kit 820400-901) 1598 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 50 mm
  • Phase
  • Eclipse XDB-C8
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L7
  • Brand
  • ZORBAX
  • Carbon Load
  • 7.6 %
  • Endcapped
  • Double
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 340 bar
  • Separation Mode
  • Reversed Phase
AGIL970100-906 ZORBAX Eclipse XDB-C8, 21.2, 100 mm, 5 µm (use with hardware kit 820400-901) 2338 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 100 mm
  • Phase
  • Eclipse XDB-C8
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L7
  • Brand
  • ZORBAX
  • Carbon Load
  • 7.6 %
  • Endcapped
  • Double
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 340 bar
  • Separation Mode
  • Reversed Phase
AGIL970150-906 ZORBAX Eclipse XDB-C8, 21.2, 150 mm, 5 µm (use with hardware kit 820400-901) 3215 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 150 mm
  • Phase
  • Eclipse XDB-C8
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L7
  • Brand
  • ZORBAX
  • Carbon Load
  • 7.6 %
  • Endcapped
  • Double
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 340 bar
  • Separation Mode
  • Reversed Phase
AGIL977250-106 ZORBAX Eclipse XDB-C8, PrepHT cartridge, 21.2, 250 mm, 7 µm (use with hardware kit 820400-901) 3333 
Add to Cart
  • Inner Diameter (ID)
  • 21.2 mm
  • Length
  • 250 mm
  • Phase
  • Eclipse XDB-C8
  • UNSPSC Code
  • 41115709
  • USP Designation
  • L7
  • Brand
  • ZORBAX
  • Carbon Load
  • 7.6 %
  • Endcapped
  • Double
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • LC Platform
  • Preparative HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 7 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 340 bar
  • Separation Mode
  • Reversed Phase
AGIL5185-5920 ZORBAX StableBond C18, 1.0 x 17 mm, 5 µm, 400 bar, guard, 3/pk. 80Å, 600 bar pressure limit 410 
Add to Cart
  • Inner Diameter (ID)
  • 1 mm
  • Length
  • 17 mm
  • Phase
  • SB-C18
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L1
  • Brand
  • ZORBAX
  • Carbon Load
  • 10 %
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Conventional
  • Maximum Temperature
  • 40 °C at pH 6-8 90 °C at pH 1-6 40 °C at pH 6-890 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 0.8-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL820950-927 ZORBAX Eclipse XDB-Phenyl, 80Å, 4.6 x 12.5 mm, 5 µm, 400 bar pressure limit, guard cartridge (ZGC), 4/pk 231 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 13 mm
  • Phase
  • Eclipse XDB-Phenyl
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L11
  • Brand
  • ZORBAX
  • Carbon Load
  • 7.2 %
  • Endcapped
  • Double
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-9 60 °C at pH 2-6 40 °C at pH 6-960 °C at pH 2-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL820950-928 ZORBAX Bonus-RP, 80Å, 4.6 x 12.5 mm, 5 µm, 400 bar pressure limit, guard cartridge (ZGC), 4/pk 230 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 13 mm
  • Phase
  • Bonus-RP
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L60
  • Brand
  • ZORBAX
  • Carbon Load
  • 9.5 %
  • Endcapped
  • Triple
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 8-9 60 °C at pH 2-8 40 °C at pH 8-960 °C at pH 2-8
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL820950-933 ZORBAX StableBond Aq, 4.6 x 12.5 mm, 5 µm, 400 bar, guard cartridge (ZGC), 4/pk. 80Å, 400 bar pressure limit 235 
Add to Cart
  • Inner Diameter (ID)
  • 4.6 mm
  • Length
  • 12.5 mm
  • Phase
  • SB-Aq
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L96
  • Brand
  • ZORBAX
  • Endcapped
  • No
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 6-8 80 °C at pH 1-6 40 °C at pH 6-880 °C at pH 1-6
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 1-8
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase
AGIL821125-928 ZORBAX Bonus-RP, 80Å, 2.1 x 12.5 mm, 5 µm, 400 bar pressure limit, guard cartridge (ZGC), 4/pk 230 
Add to Cart
  • Inner Diameter (ID)
  • 2.1 mm
  • Length
  • 13 mm
  • Phase
  • Bonus-RP
  • UNSPSC Code
  • 41115711
  • USP Designation
  • L60
  • Brand
  • ZORBAX
  • Carbon Load
  • 9.5 %
  • Endcapped
  • Triple
  • Guard Column
  • Yes
  • Hardware
  • Cartridge
  • LC Platform
  • HPLC
  • Maximum Temperature
  • 40 °C at pH 8-9 60 °C at pH 2-8 40 °C at pH 8-960 °C at pH 2-8
  • Molecular Weight Lower Limit
  • 0 Da
  • Particle Size
  • 5 µm
  • Particle Type
  • Fully Porous
  • pH Range
  • 2-9
  • Pore Size
  • 80 Å
  • Pressure Rating
  • 400 bar
  • Separation Mode
  • Reversed Phase

Overview

The small molecule column portfolio includes state-of-the-art superficially porous InfinityLab Poroshell 120 columns as well as traditional fully porous ZORBAX, Polaris, and Pursuit columns.

When you choose Agilent small molecule LC columns, you get more than just a dependable product. You also get unmatched technical support from the world’s largest chromatography supplier.


Agilent gel permeation chromatography (GPC) and size exclusion chromatography (SEC) columns and standards have been the top-selling in the polymer industry for over 40 years. GPC and SEC is used to determine the molecular weight and size distribution of macromolecules. SEC and GPC columns generate accurate, reliable data for critical polymer parameters, including dispersity (PDI), molecular weight mass average (Mw), number average (Mn), and z-average (Mz).


The importance of understanding the attributes of a biologic drug, and the processes used to create it, cannot be underestimated.  Agilent AdvanceBio LC columns are designed and produced to provide results you can be sure of when analyzing highly complex biotherapeutic molecules and monitoring their purity, potency, and other critical quality attributes.



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